Tuesday, August 28, 2012

IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)...



At Corion, we have RI IMSI™ which is supplied with imaging and a digital zoom function that allows evaluation of sperm to be carried out at high magnification.


INTRODUCTION:
  • IMSI - a new, improved technology in Infertility treatment
  • Selection of sperm cells for IVF-ICSI by intracytoplasmic morphologically selected sperm injection (IMSI)
  • IMSI enables us to select morphologically normal sperm in a semen sample with maximum abnormal sperms.
  • Selection of such sperms prior to ICSI reduces the chances of unexplained early abortions.
BENEFICIAL FOR:
  • Patients with more than 2 ICSI failures
  • Patients where there is severe male factor abnormality e.g. severe oligoasthenospermia , normal sperm count but higher percentage of abnormal sperms , elderly male partners etc
  • Recurrent first trimester aborters-here the conventional ICSI does succeed but results in early abortions
  • Patients with prolonged Unexplained Infertility
  • Couples experiencing recurrent IVF failures and/or recurrent biochemical pregnancies/miscarriages.
IMSI MAGNIFICATION:
  • The sperm in IMSI is magnified to 7000dpi
  • High-magnification (7000dpi) with high contrast and high resolution results in selection of the normal sperms from large number of abnormal sperms
  • IMSI displays chromatin compaction defects, which appear as holes inside the nucleus called 'vacuoles'.
SPERM SELECTION:
  • Selection of sperm without defects or those with fewer vacuoles increases rates of implantation/pregnancy, and reduces miscarriage rates.
  • Once the best sperm has been selected, IMSI is carried out in exactly the same way as ICSI. 

1 comment:

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