Tuesday, December 25, 2012

Wishing You All Merry Christmas & A Happy New Year!!!

Simple Joys, Little Pleasure
Laughter & Smiles In Big Measures.
Friends, Family, Togetherness, Love...
The Choicest Blessings From Above
Peace, Prosperity & Happiness Too..
All these & Many More Are Our Wishes For You!!!

Wishing You All Merry Christmas & A Happy New Year!!!

Saturday, December 15, 2012

From Australia : Our Newest Aussie Babies

It is the nature of babies to be in bliss.Corion wishes them every happiness in their future.

" There are few decisions in life as important as choosing an IVF team to entrust the development of your future child and family to.  I wanted a clinic with an impeccable reputation not only for its professionalism and success in IVF but one that had an ethical and caring approach to recruiting women as surrogates and then providing genuine support and care to them during their pregnancy.  I can attest that Dr Kadam and her team at Corion excel in all of these areas.  Indeed they provided me with the most wonderful surrogate who delivered equally wonderful twins.  Corion’s service is personalised and supportive – including after your child is born - and its professional standards are high.  Another major advantage is that Corion is located in visitor-friendly Mumbai and uses the Hiranandani Hospital, one of Asia’s finest.  I have no hesitation in recommending Dr Kadam and the team at Corion."

Friday, November 23, 2012

A New Research : Unexplained Infertility

A new research from Queen's University Belfast has uncovered the cause of 'unexplained infertility,' providing fresh hope to couples with the condition.

At present one million couples require fertility treatment across the world. Up to one third of these couples are diagnosed with unexplained or idiopathic infertility. This means that, using current tests, neither partner has been diagnosed with any detectable problem.

It is revealed that 80 per cent of couples with unexplained or idiopathic infertility in the large study of 239 couples have a detectable cause known as high sperm DNA damage.

The new study is the first of its kind and will lead to better treatment for these couples, saving them time, money and heartache.

It was studied that the majority of couples experiencing problems with fertility are able to receive an explanation for their infertility. These causes range from low sperm count, poor sperm motility in the man to blocked Fallopian tubes or endometriosis in the woman. Once the causes for infertility have been established the appropriate course of assisted conception treatment can be undertaken.

For almost one third of couples, until now, there has been no obvious cause for infertility and these couples are given the diagnosis of 'unexplained fertility," she stated.

These couples often invest a lot of time and money in fertility treatments like intrauterine insemination (IUI) unlikely to be successful, she revealed.

"In our study we have now had a breakthrough, which explains the cause of infertility for many of those couples. Now that we have found the cause of infertility for these couples suitable treatments can be tailored for them which will direct them straight to the best treatment and increase their chances of having a baby," she added.

The study also showed that the chances of having a baby after IVF is closely related to the amount of DNA damage a man has in each of his sperm. A little damage is normal (under 15 per cent per sperm), as is seen in the sperm of fertile men. But if the damage reaches clinically important levels (high sperm DNA damage more than 25 per cent per sperm) it will reduce the couples' chances of a family, even with some forms of fertility treatment.

The research was carried out using a unique test for male fertility called the Sperm Comet.

The finding was published in Reproductive Biomedicine Online.

Saturday, November 10, 2012

A New Study Showing : Chromosome Screening May Increase IVF Success In Older Mothers!!!

The study was presented at a meeting of the American Society for Reproductive Medicine (ASRM) in San Diego, USA :

Using a new IVF technique could considerably increase older women's chances of pregnancy, a small clinical trial presented at a fertility conference suggests.

In the technique embryos produced via IVF are first tested for major genetic abnormalities using a method called comprehensive chromosomal screening (CCS)

For this, samples are taken from embryos at the blastocyst stage, when they have around 100 cells. CCS tests whether embryos have the normal 46 chromosomes, 23 from each parent. The genetically normal embryos are cryopreserved for a month or two before being thawed and inserted in the womb. The cryopreservation period is thought to allow the woman’s hormones to settle after the disturbance caused by IVF drug treatment.

A randomized controlled trial in 60 patients compared the new technique against standard embryo screening, where embryo quality is assessed primarily by evaluating their appearance under a microscope.

 Although the abstract relating the findings is unclear, the Telegraph says that the CCS technique 'took the successful pregnancy rate in a group of 38 to 42-year-old from 33 to 61 percent.

The researchers also reported that none of the women implanted with embryos that had been through CCS had first trimester miscarriages, whereas six of the 30 women implanted with embryos that had been through standard screening did miscarry within the first trimester.
Also showed  it had been able to show is that a woman aged 38 to 42, if she has a blastocyst with a normal number of chromosomes, her chances of implantation are independent of her age. So she has the same chances of implantation – at 60 percent – as a woman who is 32.

The risk of producing an embryo possessing an abnormal number of chromosomes (a condition known as aneuploidy) increases as a woman ages. By the age of 40, 75 percent of a woman's embryos are aneuploid, and this heightens the risk of any resulting child having disorders like Down's syndrome and also increases the risk of miscarriage.

Monday, October 29, 2012

A Review Of A New Research : Chances Of A Successful IVF Treatment Could Be Doubled By Gently Scratching The Womb Lining!!!

Gently scratching the lining of the womb nearly a month before IVF treatment could almost double the chances of a successful treatment, according to a new study by British researchers. 

A review of research on the technique found that twice as many women became pregnant after the procedure than without, boosting pregnancy rates to almost one in two.

It is thought that scratching the womb lining stimulates growth factors and repair mechanisms that allow the fertilized egg to embed more easily. 

Endometrial scratching uses simple, inexpensive equipment & takes only 15 minutes in clinic, can be carried out by trained nurses and uses simple equipment already in use.The chance of pregnancy could be doubled.

In the review, 128 out of 499 women who did not have the womb procedure became pregnant - almost 26 percent. Of the 412 women who had the procedure, 198 fell pregnant, or 48 percent. 

There were no serious side effects reported and early signs are that the doubling in rates will be translated into birth rates. 

The women in the study had all suffered repeated unexplained implantation failure, meaning other aspects of their fertility seemed normal but the egg did not implant properly in the womb. 

This study has been published in Reproductive Biomedicine online

Saturday, October 20, 2012

A New Study Has Found That Vitamin D May Increase The Chance Of IVF Success But It Depends On A Woman's Race. .

Vitamin D, also known as the 'sunshine vitamin', is famed for its benefit to bones and the immune system, but it also plays a role in conception.

Now, data suggests that the vitamin's benefits may only apply to certain racial groups - while white women can boost their IVF success rates with vitamin D, this doesn't appear to be true for Asian women. 

In vitro fertilization (IVF) is a popular option for couples struggling to conceive - it involves extracting eggs from a woman and fertilizing them with sperms outside of the body. The resulting embryo is then transferred into the uterus. 

To find out whether vitamin D carries the same benefits in women of different races,it has been compared ; vitamin D levels and IVF success rates in white Hispanic, white non-Hispanic, and Asian women from south-east Asia and the Indian subcontinent. 

All 188 women included in the study were having IVF for the first time. 

Of these women, only 42 percent had the recommended levels of vitamin D - just over a third had insufficient levels, while a fifth were completely deficient. 

The researchers found that white women who were vitamin D replete were four times more likely to have a successful pregnancy as compared to women of the same race who were deficient in the vitamin. 

Unexpectedly, the reverse was true for Asian women as those with the lowest vitamin D levels were most likely to get pregnant. 

Even though the team aren't sure why these differences exist, they think it might have something to do with the enzyme that deactivates vitamin D. 

According to them, there are also ethnic differences in the gene for the vitamin D receptor, which may affect the link between vitamin D and conception. 

The study has been published in the journal Human Reproduction.

Wednesday, October 17, 2012

Egg Producing Cells That Survive Cancer Treatment may prevent Infertility..A New Study Shows :

In a finding that could prevent infertility among women who undergo treatment for cancer, researchers have identified new egg-producing cells that can survive the radiation caused due to cancer treatment.

The findings by researchers from Melbourne could pave the way for a course of injections or tablets able to protect women's fertility within a decade

The proteins, known as PUMA and NOXA, trigger death in damaged cells in the ovaries.

Researchers established a way to prevent the proteins reaching the damaged cells, thereby keeping the cells alive.

They were also able to show for the first time that the cells were able to repair the damage caused to their DNA by cancer treatment - and go on to produce healthy offspring.

The study has been published in the journal Molecular Cell.

Sunday, September 9, 2012

Corion Fertility Clinic recent article published in The Sun !!!

Indian surrogate gave us babies we dreamed 

of... in return we changed her life

Chris and Joanne McDuff with Imogen and Andrew

Our bundles of joy ... Chris and Joanne with 7-month-old twins Imogen and Andrew

Published: 05th September 2012


Monday, September 3, 2012

Recent Study : Full Chromosomal Testing Significantly Increases IVF Pregnancy Rates

One of the recent studies shows that full chromosomal testing Significantly increases IVF Pregnancy rates :

The results of the first randomized study into a form of Preimplantation Genetic Diagnosis (PGD) testing, 24Sure Array CGH (comparative genomic hybridization) technology, has found it significantly increases the pregnancy rates in IVF patients.

Published in May in the Journal of Molecular Cytogenetics, the American study found that 24Sure Array CGH technology delivers a 65% increase in pregnancy rates, even in younger patients with more favorable IVF outcomes.
Dr Leeanda Wilton, Scientific Director, Preimplantation Genetics for Melbourne IVF and IVF Australia welcomed the study, stating the results mirror the Advanced Embryo Selection successes.
Advanced Embryo Selection, using the 24Sure Array CGH technology, screens all 24 chromosomes in a developing embryo, which is a significant advance on earlier forms of PGD testing that only screened 8 out of 24 chromosomes.  A single cell is biopsied (removed) from the embryo on day three of development in the laboratory, and the DNA from the cell’s nucleus is multiplied thousands of times before being placed on a microarray, or DNA chip, where it is compared with normal male and female DNA. This allows the accurate detection of chromosome errors, increasing the chance of a healthy baby resulting from the transfer of a chromosomally normal embryo.
“Using Advanced Embryo Selection, testing can be performed on a single cell from a day 3 embyro, whereas similar forms of technology require embryos to develop to the blastocyst stage on day 5 in order for several cells to be available for testing,” Dr Wilton said.
“About 50% of all embryos fail to reach the blastocyst stage on day 5, and this means a number of patients have no embryos that can be tested.  Some of these embryos are viable and can result in live births.
“Advanced Embryo Selection also provides accurate results within 30 hours, meaning patients can undertake a fresh embryo transfer, and their treatment can continue uninterrupted, whereas in most cases embryos that need to be biopsied on day 5 must be frozen because the results are not available in time to perform a fresh embryo transfer.
Advanced Embryo Selection is most suited to couples or single women where:
  • 5 or more embryos have been replaced without success,
  • the woman is aged 38 or more
  • there is a history of recurrent miscarriage
  • there has been a previous pregnancy with a chromosome error e.g. Down syndrome
Study Reference:  The Journal of Molecular Cytogenetics by Yang et al 2012, 5:24 (2 May 2012)

Tuesday, August 28, 2012

IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)...

At Corion, we have RI IMSI™ which is supplied with imaging and a digital zoom function that allows evaluation of sperm to be carried out at high magnification.

  • IMSI - a new, improved technology in Infertility treatment
  • Selection of sperm cells for IVF-ICSI by intracytoplasmic morphologically selected sperm injection (IMSI)
  • IMSI enables us to select morphologically normal sperm in a semen sample with maximum abnormal sperms.
  • Selection of such sperms prior to ICSI reduces the chances of unexplained early abortions.
  • Patients with more than 2 ICSI failures
  • Patients where there is severe male factor abnormality e.g. severe oligoasthenospermia , normal sperm count but higher percentage of abnormal sperms , elderly male partners etc
  • Recurrent first trimester aborters-here the conventional ICSI does succeed but results in early abortions
  • Patients with prolonged Unexplained Infertility
  • Couples experiencing recurrent IVF failures and/or recurrent biochemical pregnancies/miscarriages.
  • The sperm in IMSI is magnified to 7000dpi
  • High-magnification (7000dpi) with high contrast and high resolution results in selection of the normal sperms from large number of abnormal sperms
  • IMSI displays chromatin compaction defects, which appear as holes inside the nucleus called 'vacuoles'.
  • Selection of sperm without defects or those with fewer vacuoles increases rates of implantation/pregnancy, and reduces miscarriage rates.
  • Once the best sperm has been selected, IMSI is carried out in exactly the same way as ICSI. 

Wednesday, August 22, 2012

An Article In The Latest Issue : Egg Stem Cells Are Lurking in Your Ovaries!!!

An article in the latest issue of Nature Medicine has everyone in the infertility community buzzing. Researchers say they have isolated rare stem cells in women's ovaries that have the capability of creating new eggs.

Women are born with a lifetime of eggs and do not produce additional eggs as they age. (Men, on the other hand, produce sperm continually at an average of 100 million a day.) An average woman's body matures and releases one egg during each monthly menstrual cycle from menarche (her first cycle) until menopause (when her menstrual cycles have stopped). A woman's fertility begins to decline relatively early in her lifespan; by age 25, fertility begins to decrease. By age 30, her ovarian reserve is down to 12%, meaning most of her eggs gone.

In this latest study led by Jonathan Tilly, director of the Vincent Center for Reproductive Biology at Massachusetts General Hospital, the researchers built upon previous research done in mice, in which they were able to isolate the egg stem cells, mature them in vitro and produce eggs. Tilly's earlier work found proteins on the stem cells that distinguished them from other types of cells. These same proteins were found in women, the cells were isolated and grown, and then added back to the ovarian tissue samples and then transplanted into a mouse, where immature eggs began to grow.

The news is exciting, offering promise to women whose own eggs are not viable or are simply gone due to age.

Tuesday, August 7, 2012

From Spain !!!

Our history stars at the summer of  2010, we saw good references from spanish people about Corion Fertility Clinic and specially of the Dra Kadam.
We contact with her, and she takes a lot of time to explain  us the process and how much it could cost.
When we go first time to  Corion Fertility Clinic we talk with her and we come back to hotel really surprised with the gullibility and humanity of Dra Kadam.
Our first try ( with twins) failed at the second month of pregnancy, but the dra kadam phone us and told that at the second try she would do all for the success.
At second time we get a twin pregnacy again, and this time we get it, two wonderful babies called Alvaro and Maria.
The Hospital Hiranandani is one of the best of mumbai, and we really were surprised, becouse it seems like a European Hospital, and better that much of them.
The only problem was with the legal process, but Dra Kadam help us with that again.
We are really happy with the  Corion Fertility Clinic and all the people who ask us in Spain we recommend  it, if we have to do it again we will do it with the Dra kadam...

Monday, July 16, 2012

From Australia: A Beautiful Baby Girl

"Dreams do come true and our miracle was born, a beautiful baby girl!!!! Her name meaning "our precious gift from India". At such an overwhelming time in our lives, the emotional roller-coaster of creating our family was made so much easier with thanks to Dr Kadam and the Corion Clinic. They were such an amazing help along our entire journey! They were absolutely fantastic in every way possible - very friendly, supportive, helpful and extremely professional. From egg retrieval, embryo transfer to the regular ultrasound updates and pregnancy resulting in our precious baby daughter, the whole process was a very positive and memorable one. Now, a year on, with our miracle growing and developing so happy and healthy, we cannot thank Dr Kadam and her crew enough for the joy they have brought to our lives!!!! Thank you, thank you, thank you!!!"

Warm Regards..

Monday, July 9, 2012

Tuesday, June 26, 2012

From Australia : A Baby Boy

Congratulations to our Australian Parents

"We have known Dr Kadam for the past 2 years. During this time she has blessed us with a beautiful baby boy for which we will always be grateful for. A gestational surrogate carried our baby for us and throughout the whole pregnancy we were regularly informed of our babys progress. Dr Kadam has been great at answering all my questions and putting my mind at ease while maintaining a high level of professionalism and integrity.
It’s Dr Kadams extensive medical experience and warm caring nature that makes Corion different from other fertility clinics in both India and Australia"

Dr.Kadam with the proud Australian Parents

Wednesday, February 22, 2012

Australian Couple Blessed with Twin Babies in Feb'12

This family from Australia been blessed with twin...

To ,
The entire team of Corion. Thank you so much for turning our dream of having a family into reality. You have given us two perfect angels : a boy and a girl
Our entire experience has been wonderfull and we offer you our deepest gratitude.
If anyone has any questions about the process we are happy   to help any way we can - they can email -  inekek_6@hotmail.com
Warm Regards...

Tuesday, February 14, 2012

Semen Freezing...

Semen Freezing is advised when the husband is not available at the time of infertility treatment [staying abroad or travelling]. As a back up when the husband is worried that he may not be able to produce a semen sample on the required day due to anxiety/stress. Semen freezing is requested in men suffering from malignancies prior to exposure to chemotherapy or radiation, which will affect sperm production. 
Details for Sperm Banking can be read at :  http://www.corionfertilityclinic.com/semen-cryopresrvation.php

Semen Cryopreservation

Thursday, January 12, 2012

Australian Couple Blessed with an Angel ' January 2012


“My husband and I have just returned from India with our beautiful Baby Girl, Lilah.

Our journey of 9 years led us to Corion Fertility Clinic and we are so grateful to 

Dr Kadam and her staff for helping us to become a family. After meeting with 

Dr Kadam it is very clear her compassion towards her intended parents and 

surrogates is why she has been so successful in her chosen field.Dr Kadam 

was more than happy to answer any questions we had and assist us in any 

way she could. We both highly recommend her and her staff and would be 

happy to share our experience with anyone contemplating using 

Corion Fertility Clinic.”